C.STIM

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Multiple mechanisms of action with C.STIM® IPL therapy
An elegant design for ease of use
4 clinical strengths of C.STIM®
Media Library
Take full advantagewith a wide range of accessories
Testimonials
How to include the C.STIM® IPLin your therapeutic arsenal?
Case Studies
Want to know more?

C.STIM®, IPL SYSTEM
FOR DRY EYE TREATMENT

IPL (Intense Pulsed Light) C.STIM® technology is a premium, safe and efficient IPL system dedicated to treat the root causes of dry eye disease. This revolutionary IPL, specifically dedicated to Ophthalmic Uses, integrates patented homogeneous light and unique pulse train to offer the best combination of clinical efficacy and patient comfort.

*Not FDA approved

Key Features

Treatment of the root causes of dry eye: MGD, inflammation, Demodex and neuropathic pain
Quick and easy treatment (<10 min)
Safe and efficient treatment thanks to the unique handpiece with an optical tip incorporating the Stim-ULI™ technology (Uniform Light Intensity) and the train of 5 regulated pulses.
Treatment on the majority of skin types thanks to the light spectrum, the train of 5 regulated pulses and to the water cooling of the handpiece.

Multiple mechanisms of action
with C.STIM® IPL therapy

Meibomian Gland Dysfunction (MGD)

IPL speeds up Meibomian Gland and lacrimal gland metabolism by stimulating the parasympathetic nervous system thanks to the IPL energy stimulation.
IPL liquefies the thick meibum thanks to the heat generated by IPL light.
After IPL session, a manual meibomian gland expression, by pressing the tarsus with a meibomian forceps is important to increase the long-term effectiveness of IPL treatment and to relieve some signs and symptoms of Dry Eye.

Inflammation

IPL stoppes the vicious cycle of chronic inflammation by coagulating new blood vessels of the skin and the eyelids, and by reducing inflammatory agents in the tears.
The telangiectasias being smaller at the level of the eyelids, the IPL flash will have a localized heating effect at the level of the vessels and around the vessels. This effect modulates their function and changes their temperature.
Studies have shown that in cases of blepharitis, the number of telangiectasias in the eyelids decreased after IPL sessions.

Demodex

Demodex is associated with facial and ocular rosacea. The parasite is a component of MGD, which is part of inflammatory vicious cycle.
Demodex Infestation leads to physical obstruction of meibomian glands and then causes obstructive meibomian gland dysfunction (MGD).
The pigmented exoskeleton of Demodex absorbs the energy of IPL leading to the Demodex destruction, and inflammatory markers are reduced.

<p><br>An elegant design <br><strong>for ease of use</strong></p>

An elegant design
for ease of use

With its large HD touch screen, C.STIM has an intuitive software with an access to the treatment page in 2 clicks.

It integrates pulse pre-settings dedicated to dry eye treatment to ensure safety and simplicity of use on the majority of skin types.

4 clinical strengths of C.STIM®

Patented Stim-ULI™ technology

Safe and effective treatment with Stim-ULI™

Our C.STIM® revolutionary IPL relying on our unique Stim-ULI™ (Uniform Light Intensity) technique offers the best combination of clinical efficacy and patient comfort.

Unique train of 5 regulated pulses

Better results, no side effects, comfortable

Respects the skin's thermal relaxation time (TRT)
No thermal damage to the skin
No inflammatory reaction
Controlled energy accumulation for better results

Optimised handpiece

Single handpiece with integrated water-based cooling system

Improved patient comfort
Applies a thin layer of gel during treatment
Delivers the same energy level from first to last shot
Optimal preservation of flash lamp life: 30 000 shots/3 750 sessions

Treatment on the majority of skin types

Safe and effective treatment for phototypes 1 to 5

Light spectrum of 610 nm to 1 200 nm is less absorbed by melanin
Energy controlled by pulse train, limiting increase in tissue temperature
Stim-ULI™ technology for a perfectly homogeneous energy distribution

Media Library

Access to all our clinical data

Take full advantage
with a wide range of accessories

Patient protective intraocular scleral shell

Testimonials

Dr Wojciech Adamski Poznań, Polska

C.STIM is a small revolution in the treatment of patients with dry eye disease associated with meibomian gland dysfunction. It allows a painless, quick, and most importantly, effective improvement of the functioning of the eyelid margins and significantly improves the patients' quality of life. After a series of sessions, patients report an improvement in the quality of life and I am very pleased to use dedicated ophthalmic devices using the IPL technology proven in medicine.

Dr Pieter Gouws Spire Sussex Hospital, UK

I have had excellent feedback from patient whom I have treated with the IPL device from Quantel Medical. It is important to manage expectations and I tell my patients to expect a noticeable improvement after 3 treatments. I am recommending 4 treatments for all cases and the typical response is an improvement in symptoms which last longer and longer after each treatment. Re-treatment with 1 session is often requested at about 1 year after the first treatment. I highly recommend this IPL for it’s ease of use and excellent training and backup provided by the suppliers.

Dr Serge Doan Bichat Hospital and Rothschild Fondation, Paris, France

I use the C.STIM IPL mainly for meibomian dysfunctions. When there is inflammation or demodex of the eyelids, I use IPL directly on the eyelids with metal palpebral shells, a protocol that studies have shown works better than periocular flashes. Patients with neuropathic pain also experience improvement after IPL sessions.

Marie-Caroline Trone Saint-Etienne, France

We have been using Quantel Medical IPL devices for several years, first LACRYSTIM and more recently C.STIM.
It is quite natural that these IPL devices have found their place in our daily practice within our consultation dedicated to dry eyes. The number of patients treated increases every year.
C.STIM is very easy to use and does not require any consumables. A session lasts only a few minutes and is perfectly painless.
The different doctors of the department have quickly adopted it, as well as the patients!

Dra. Adriana Abreu Di Luigi "El Viñedo" Ophthalmology Clinic (Venezuela)

It has truly been a before and after in the management of patients with dry eye disease, hyper evaporative, meibomitis, blepharitis, meibomian gland dysfunction and other ocular surface diseases. It is really satisfying for me as well as for the patients themselves to see the results after the treatment, in terms of improvement of their quality of life, tear film quality and visual quality.

How to include the C.STIM® IPL
in your therapeutic arsenal?

IPL is now part of the therapeutic arsenal for dry eye.
Review the case study below to learn how it can be used to complement other dry eye treatments.

Clinical cases by our experts

Because patient care is at the heart of our concerns, it is important to collect the experience of doctors who use our products.

Access to all our clinical cases

Want to know more?

How to communicate with dry eye patients?

To help you develop your dry eye business, Quantel Medical has developed a complete kit of communication tools dedicated to patients, both in paper and digital versions.

We have created this kit is the result of a simple fact that dry eye is a new pathology that still too little known, for which patients need information.

They need dedicated materials to give them a clear understanding of the pathology and its causes, symptoms, diagnosis and treatment options.

For you, as healthcare professionals, educational materials are also important to highlight this speciality when patients arrive in your waiting room and also to help you recruit new patients.

Learn more

WANT TO DEMO C.STIM®?

Lumibird Medical participates in many events throughout the year.

Find in our Events section the next congresses in which we will participate and come, visit us on our booth to test our products!

Learn more

What are the principles of inten...

17/11/2022

IPL technology has been used in dermatology since 1994 to treat of various pathologies, including skin rosacea, acne, vasc...

How to organise your dry eye con...

17/11/2022

In recent years, more and more patients have been complaining of the same symptoms: itchy, scratchy eyes and gritty feelin...

How can I include the IPL system...

17/11/2022

Dry eye is a multifactorial pathology that affects the surface of the eye and the eyelids. There are different forms of d...

Model still available in some countries according to local registration: LacryStim
For further information, please contact us.

Bibliography :

1. Parasympathetic Innervation of the Meibomian Glands in Rats – Mark S. LeDoux et al. – Investigative Ophthalmology & Visual Science, October 2001, Vol. 42, No. 11.
2. Characterization of the innervation of the meibomian glands in humans, rats and mice – Bründl, M. et al. Annals of Anatomy (2021), Vol. 233.
3. Neurotransmitter Influence on Human Meibomian Gland Epithelial Cells – Wendy R. Kam and David A. Sullivan – Investigative Ophthalmology & Visual Science, November 2011, Vol. 52, No. 12.
4. The Dopaminergic Neuronal System Regulates the Inflammatory Status of Mouse Lacrimal Glands in Dry Eye Disease – Ji, Yong Woo et al. Investigative Ophthalmology & Visual Science (2021), Vol. 62.
5. TFOS DEWS II Pathophysiology Report – Anthony J. Bron, et al. – The Ocular Surface, 2017, p 441 to 515.
6. The neurobiology of the meibomian glands – Cox SM, Nichols JJ – Ocular Surface, July 2014.
7. Multicenter Study of Intense Pulsed Light Therapy for Patients with Refractory Meibomian Gland Dysfunction – Reiko Arita, et al. – Cornea Volume 37, Number 12, December 2018.
8. Rosacea: Molecular Mechanisms and Management of a Chronic Cutaneous Inflammatory Condition – Yu Ri Woo, et al. International Journal of Molecular Sciences, September 2016.
9. Rosacea: Epidemiology, pathogenesis, and treatment – Barbara M. Rainer et al. – DERMATO-ENDOCRINOLOGY 2018, VOL. 9, NO. 1, e1361574 (10 pages).
10. Treatment of ocular rosacea – Edward Wladis et al. – Survey of Ophthalmology (2018), Vol. 63.
11. Improved telangiectasia and reduced recurrence rate of rosacea after treatment with 540 nm-wavelength intense pulsed light: A prospective randomized controlled trial with a 2-year follow-up – Luo, Y. et al. – Experimental and Therapeutic Medicine (2020), Vol. 19.
12. Therapeutic Effect of Intense Pulsed Light on Ocular Demodicosis – Zhang, X., et al. – Current Eye Research 2019, Vol. 3.
13. Intense Pulsed Light Therapy for Patients with Meibomian Gland Dysfunction and Ocular Demodex Infestation – Cheng et al. – Current Medical Sciences (2019), Vol. 39.
14. Long-term effects of intense pulsed light treatment on the ocular surface in patients with rosacea-associated meibomian gland dysfunction – Seo Kyoung Yul et al. – Contact Lens and Anterior Eye (2018), Vol. 41.
15. TFOS DEWS II Tear Film Report – Willcox Mark et al. – The Ocular Surface (2017), Vol. 15.
16. Intense Pulsed Light for the Treatment of Dry Eye Owing to Meibomian Gland Dysfunction – Vigo, L. et al. – Journal of Visualized Experiment (2019), N°146.
17. Meibum Expressibility Improvement as a Therapeutic Target of Intense Pulsed Light Treatment in Meibomian Gland Dysfunction and Its Association with Tear Inflammatory Cytokines – Choi, M. et al. – Scientific Reports (2019), Vol. 9.
18. TFOS DEWS II Pain and Sensation Report – Belmonte Carlos, et al. – The Ocular Surface (2017), Vol. 15.
19. Analysis of Cytokine Levels in Tears and Clinical Correlations After Intense Pulsed Light Treating Meibomian Gland Dysfunction – LIU, R et al. – American Journal of Ophthalmology (2017).
20. Effect of inflammation on lacrimal gland function – Driss Zoukhri – Experimental Eye Research, May 2006; 82(5): 885–898.
21. Aqueous deficiency is a contributor to evaporation-related dry eye disease – Charles W. McMonnies – Eye and Vision (2020) 7:6.
22. A retrospective study of the efficacy of intense pulsed light delivered by the Lacrystim® for meibomian gland dysfunction therapy - Marie‑Caroline Trone et al. - BMC Ophthalmology (2022) 22:335

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C.STIM®, IPL SYSTEM FOR DRY EYE TREATMENT

Multiple mechanisms of action with C.STIM® IPL therapy

Meibomian Gland Dysfunction (MGD)

Inflammation

Demodex

An elegant design for ease of use

4 clinical strengths of C.STIM®

Patented Stim-ULI™ technology

Safe and effective treatment with Stim-ULI™

Unique train of 5 regulated pulses

Better results, no side effects, comfortable

Optimised handpiece

Single handpiece with integrated water-based cooling system

Treatment on the majority of skin types

Safe and effective treatment for phototypes 1 to 5

Media Library

Take full advantagewith a wide range of accessories

Testimonials

How to include the C.STIM® IPLin your therapeutic arsenal?

Clinical cases by our experts

C.STIM®, IPL SYSTEM
FOR DRY EYE TREATMENT

Multiple mechanisms of action
with C.STIM® IPL therapy

An elegant design
for ease of use

Take full advantage
with a wide range of accessories

How to include the C.STIM® IPL
in your therapeutic arsenal?